Statistical analysis and graphical representation for biomedical and bioinformatics studies

R-project
Free
Offline
http://www.r-project.org/

R provides a wide variety of statistical (linear and nonlinear modelling, classical statistical tests, time-series analysis, classification, clustering, …) and graphical techniques, and is highly extensible. The S language is often the vehicle of choice for research in statistical methodology, and R provides an Open Source route to participation in that activity.